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Peter M Blumberg Selected Research

Induced Hypothermia

12/2020Discovery of 1-(1H-indazol-4-yl)-3-((1-phenyl-1H-pyrazol-5-yl)methyl) ureas as potent and thermoneutral TRPV1 antagonists.
11/2015Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists.
8/20142-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists.
8/20142-Aryl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists.
10/20122-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent transient receptor potential vanilloid 1 (TRPV1) antagonists: structure-activity relationships of 2-amino derivatives in the N-(6-trifluoromethylpyridin-3-ylmethyl) C-region.

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Peter M Blumberg Research Topics

Disease

26Neoplasms (Cancer)
01/2018 - 09/2002
16Pain (Aches)
01/2021 - 06/2003
7Alzheimer Disease (Alzheimer's Disease)
01/2017 - 01/2003
6Hyperthermia
12/2020 - 02/2009
5Hyperalgesia
01/2020 - 08/2002
5Neuralgia (Stump Neuralgia)
01/2020 - 08/2014
5Leukemia
01/2018 - 02/2010
5Prostatic Neoplasms (Prostate Cancer)
06/2014 - 01/2002
4Inflammation (Inflammations)
01/2016 - 08/2002
4Glioma (Gliomas)
06/2008 - 01/2002
3Infections
07/2003 - 06/2002
2Lung Neoplasms (Lung Cancer)
01/2019 - 01/2018
2Hyperplasia
12/2016 - 01/2003
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2016 - 03/2006
2Melanoma (Melanoma, Malignant)
06/2014 - 11/2011
2Neurogenic Inflammation
04/2013 - 01/2013
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2006 - 02/2003
2Lymphoid Leukemia
03/2004 - 09/2002
1Dementia (Dementias)
01/2018
1Acidosis
01/2016
1Neuroinflammatory Diseases
01/2016
1Adenocarcinoma
04/2014
1Breast Neoplasms (Breast Cancer)
04/2014
1Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2013
1Disease Progression
01/2013
1Colonic Neoplasms (Colon Cancer)
02/2010
1Carcinoma (Carcinomatosis)
05/2009
1Lymphoma (Lymphomas)
01/2009
1Hypersensitivity (Allergy)
07/2008
1Myotonic Dystrophy (Dystrophia Myotonica)
04/2008
1Amyloid Plaque
03/2006
1Sensation Disorders
05/2004

Drug/Important Bio-Agent (IBA)

14Protein Kinase CIBA
01/2019 - 01/2002
12Capsaicin (Zostrix)FDA Link
12/2020 - 05/2004
12Phorbol EstersIBA
01/2019 - 01/2002
10Proteins (Proteins, Gene)FDA Link
01/2018 - 07/2003
9LigandsIBA
11/2019 - 01/2003
7bryostatin 1IBA
12/2016 - 07/2006
6Analgesics (Analgesic Drugs)IBA
01/2021 - 08/2014
5DiglyceridesIBA
05/2014 - 01/2002
4LactonesIBA
01/2019 - 01/2002
4BryostatinsIBA
01/2018 - 06/2011
4CationsIBA
03/2015 - 12/2007
3Formaldehyde (Formol)FDA Link
01/2021 - 03/2016
3TRPV1 receptorIBA
01/2013 - 06/2003
3Protein Kinases (Protein Kinase)IBA
07/2008 - 04/2008
3Amyloid Precursor Protein Secretases (beta-Secretase)IBA
03/2006 - 01/2003
2IsoenzymesIBA
01/2019 - 05/2009
2phorbolIBA
01/2019 - 12/2016
2lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
01/2018 - 01/2013
2Merle 23IBA
12/2016 - 06/2011
2ras ProteinsIBA
01/2015 - 04/2014
2Protein Isoforms (Isoforms)IBA
06/2014 - 02/2003
2Phosphatidylinositols (Phosphatidylinositol)IBA
11/2011 - 08/2002
2AndrogensIBA
10/2010 - 01/2002
2TRPV Cation ChannelsIBA
02/2009 - 04/2008
2Therapeutic UsesIBA
01/2009 - 05/2007
2Etoposide (VP 16)FDA LinkGeneric
06/2008 - 01/2002
2Amyloid (Amyloid Fibrils)IBA
03/2006 - 03/2006
2Tyrosine (L-Tyrosine)FDA Link
06/2005 - 06/2002
2Growth InhibitorsIBA
03/2004 - 09/2002
1Opioid Analgesics (Opioids)IBA
11/2019
1Myristic Acid (Tetradecanoic Acid)IBA
01/2019
1Acetates (Acetic Acid Esters)FDA Link
01/2019
1CarcinogensIBA
12/2016
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
01/2016
1LipidsIBA
01/2016
1Calcium Channels (Calcium Channel)IBA
01/2016
1neristatin 1IBA
04/2015
1Guanine NucleotidesIBA
06/2014
1Trastuzumab (Herceptin)FDA Link
04/2014
1Messenger RNA (mRNA)IBA
04/2014
1TamoxifenFDA LinkGeneric
04/2014
1ras Guanine Nucleotide Exchange FactorsIBA
04/2014
1CalciumIBA
01/2013
1Guanosine Triphosphate (GTP)IBA
11/2011
1Epidermal Growth Factor (EGF)IBA
11/2011
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
11/2011
1AgarIBA
11/2011
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2011
1Ether (Diethyl Ether)IBA
02/2010
1beta-chimaerinIBA
09/2009
1Phosphotransferases (Kinase)IBA
04/2008
1Local AnestheticsIBA
12/2007
1QX-314IBA
12/2007
1Protons (Proton)IBA
05/2007
1Freund's AdjuvantIBA
05/2007
1Amyloid beta-PeptidesIBA
03/2006
1Peptides (Polypeptides)IBA
03/2006
1ElementsIBA
03/2006
1CaspasesIBA
06/2005
1Nerve Growth Factors (Neurotrophins)IBA
05/2004
1Anti-Bacterial Agents (Antibiotics)IBA
03/2004
11,4- bis(benzyl)- 8,9- dimethoxy- 4H- benzo(de)(1,6)naphthyridin- 1- iumIBA
03/2004
1SaltsIBA
03/2004
1Ammonium CompoundsIBA
03/2004

Therapy/Procedure

5Induced Hypothermia
12/2020 - 10/2012
4Therapeutics
04/2013 - 07/2003
2Drug Therapy (Chemotherapy)
12/2016 - 06/2014
1Oral Administration
01/2018